Sands China, a subsidiary of Las Vegas Sands, has secured $1.75bn funding for the completion of the Cotai Strip development in Macau.
The combined Shangri-La Hotels and Sheraton resort complex will add 6,000 hotel rooms.
The first phase of the development features 3,700 hotel rooms and suites from the Shangri-La and Sheraton hotel brands.
Additional retail, gaming and meeting facilities will also be added before the scheduled opening in 2011.
Phase II includes a 2,300-room Sheraton hotel tower, which will open in 2012.
The third phase includes plans for a St Regis hotel and serviced apartments will be announced at a later date.