Located at 1020 Hawthorne Avenue, the six-story hotel features 121 contemporary and sophisticated guest rooms.
Other guest amenities include multi-purpose indoor spaces and onsite dining offering local craft beer, wine and specialty cocktails, as well as to-go options.
Cambria Hotel Minneapolis Downtown also boasts multi-function meeting and event spaces as well as an advanced fitness centre.
Choice Hotels upscale brands senior vice-president Janis Cannon said: “The Minneapolis-St. Paul area has it all: a flourishing corporate community, a diverse workforce, and a world-class arts and cultural scene.
“It’s easy to see why so many Fortune 500 companies are proud to call the Twin Cities home, and why it’s an ideal location to expand Cambria’s upscale offerings to even more travellers in the region.
“Whether they’re in town for a weekend getaway or a week-long business trip, we know the Cambria Hotel Minneapolis Downtown, like the rest of our Minneapolis portfolio, will surprise and delight visitors with tailored amenities and curated design in an unbeatable location to help make the most of their time in the City of Lakes.”
Cambria Hotel Minneapolis Downtown was developed by Hawkeye Hotels and JR Hospitality.
It complements the brand’s two other properties in the city including Cambria Hotel Minneapolis Maple Grove and Cambria Hotel Bloomington Mall of America Minneapolis Airport.
The hotel is located in the centre of the city’s Gateway District and is a short drive to Target Centre, US Bank Stadium and the University of Minnesota campus.
As of 30 September 2022, Cambria Hotels has more than 60 hotels open across the US with nearly 70 hotels in the pipeline.
Last month, the brand opened Cambria Hotel Manchester South Windsor, its second property in Connecticut, US.