Financial details of the transaction have not been disclosed.
Located at 400 Sherburn Lane, the three-star Hilton Garden Inn hotel features 150 guest rooms and suites.
The rooms are equipped with several amenities, such as in-room drinks and snacks, microwave, refrigerator, Keurig coffeemaker, work area, HDTV, premium Wi-Fi and more.
The hotel also features an onsite restaurant Garden Grille & Bar that serves cooked-to-order breakfast, dinner and cocktails, sleek furnishings, a heated indoor pool, a spacious lobby and a business centre.
In addition, it boasts 2,000ft2 event space across two meeting rooms and a complimentary parking, a 24-hour sundry and convenience store as well as a 24-hour fitness centre.
Hilton Garden Inn is located minutes from the Churchill Downs, home of the Kentucky Derby.
It takes only ten minutes to reach the hotel from Louisville International Airport and 15 minutes to downtown Louisville.
MCR has a $4.0bn portfolio of 110 premium-branded hotels with over 15,000 guestrooms across 33 states and 75 cities in the US.
With 3,600 team members, it operates hotels under 12 Marriott and Hilton brands in the country.
Last month, MCR completed several purchases including the three-star Hilton Garden Inn Beaufort hotel, 114-room Homewood Suites by Hilton Dallas/Allen in Texas and more.